ED guide · Medication

Tadalafil (generic Cialis): dose, timing and price

Tadalafil is the active ingredient in Cialis. The Cialis label starts as-needed use at 10 mg before sex and reports better erections than placebo for up to 36 hours after a dose. Daily use starts at 2.5 mg. Mendoxa's compounded tablet combines tadalafil with sildenafil and apomorphine, from $129 a month.

Start your ED visit From $129/month. If prescribed · Cancel anytime · Available in 49 states (not California).

Man in his forties at home, the kind of patient who starts a private online ED visit

What the Cialis label says

Label itemAs neededOnce daily
Starting dose10 mg before sexual activity2.5 mg at about the same time each day
Range5 mg to 20 mg2.5 mg, may increase to 5 mg
FrequencyNot more than once per dayOnce a day, without regard to timing of sex
Effect windowBetter than placebo up to 36 hours after a doseDaily dosing
FoodWithout regard to foodWithout regard to food

The label lists peak level at 30 minutes to 6 hours (median 2 hours) and a mean half-life of 17.5 hours. Some sexual stimulation is needed.

0 h 4 h 12 h 24 h 36 h Viagra (sildenafil) Take 30 min to 4 h before sex; usually about 1 h. Peak 30–120 min. Half-life about 4 h. Cialis (tadalafil) Peak 30 min to 6 h (median 2 h). Half-life 17.5 h. Effect vs placebo up to 36 h.
Viagra and Cialis labels. Bars show label windows, not guaranteed erection time.

What is Cialis used for?

The Cialis label lists three uses: erectile dysfunction, the signs and symptoms of benign prostatic hyperplasia (BPH), and both together. Mendoxa's visit is for ED only.

Mendoxa ED plans and prices

The Mendoxa ED tablet is a compounded rapid-dissolve tablet with sildenafil (the active ingredient in Viagra), tadalafil (the active ingredient in Cialis) and apomorphine. It dissolves under the tongue. The Mendoxa ED page lists a maximum of 1 dose per 24 hours. A licensed clinician decides if it fits you and selects the strength. Compounded medicines are not FDA-approved.

Plan1-month planPer tablet3-month planPer tablet (3 months)
6 tablets / month$129$21.50$329$18.28
10 tablets / month$149$14.90$379$12.63
20 tablets / month$179$8.95$449$7.48

If prescribed · Cancel anytime · Available in 49 states (not California). Prices from the Mendoxa intake at try.mendoxa.co/f/ed on Oct 17, 2026. The intake always shows the current price.

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Tadalafil side effects

Most common side effects (2% or more) on the Viagra label: headache, flushing, dyspepsia, abnormal vision, nasal congestion, back pain, myalgia, nausea, dizziness and rash. On the Cialis label: headache, dyspepsia, back pain, myalgia, nasal congestion, flushing and pain in limb.

On the Cialis label, back pain or muscle aches usually started 12 to 24 hours after a dose and typically resolved within 48 hours. Drinking 5 units of alcohol or more with Cialis may lower blood pressure.

Who should not take tadalafil

The Viagra and Cialis labels list the same hard stops. Do not use them with organic nitrates in any form, or with a guanylate cyclase stimulator such as riociguat. Do not use them if sex is inadvisable because of your heart. Get emergency care for an erection that lasts more than 4 hours. Stop and get care for a sudden loss of vision in one or both eyes, or a sudden decrease or loss of hearing.

If a nitrate is ever needed in an emergency, the label says at least 48 hours should pass after the last Cialis dose.

FAQ

What is tadalafil?

Tadalafil is a PDE5 inhibitor and the active ingredient in Cialis. Its label covers ED and BPH.

How long does tadalafil last?

The Cialis label reports better erections than placebo for up to 36 hours after a dose. The mean half-life is 17.5 hours.

What is the usual tadalafil dose?

As needed: start 10 mg, range 5 to 20 mg, once a day at most. Daily: 2.5 mg, up to 5 mg. The clinician decides.

What are tadalafil side effects?

Headache, indigestion, back pain, muscle aches, nasal congestion, flushing and limb pain are the most common on the label.

How much does tadalafil cost with Mendoxa?

Mendoxa's compounded tablet with tadalafil, sildenafil and apomorphine costs $129 for 1 month, or about $7.48 per tablet on the 3-month plan.

Start your ED visit: plans and prices

The Mendoxa ED tablet is a compounded rapid-dissolve tablet with sildenafil (the active ingredient in Viagra), tadalafil (the active ingredient in Cialis) and apomorphine. It dissolves under the tongue. The Mendoxa ED page lists a maximum of 1 dose per 24 hours. A licensed clinician decides if it fits you and selects the strength. Compounded medicines are not FDA-approved.

Plan1-month planPer tablet3-month planPer tablet (3 months)
6 tablets / month$129$21.50$329$18.28
10 tablets / month$149$14.90$379$12.63
20 tablets / month$179$8.95$449$7.48

If prescribed · Cancel anytime · Available in 49 states (not California). Prices from the Mendoxa intake at try.mendoxa.co/f/ed on Oct 17, 2026. The intake always shows the current price.

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About Mendoxa

Mendoxa (mendoxa.co) is a US telehealth brand. Licensed clinicians in the LocumTele network review each online visit, and prescriptions are filled by Rush Pharmacy, a licensed US pharmacy. Available in 49 states (not California).

  • A licensed clinician reviews every visit and can say no. A prescription is not automatic.
  • A compounded medicine is not an FDA-approved finished product.
  • Plans: 1 month or 3 months, from $129. If prescribed · Cancel anytime · Available in 49 states (not California).
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Compounded medication prescribed only if a licensed U.S. clinician decides it is appropriate. Not FDA-approved as a finished product. Not available in California. This site is not for emergencies. Call 911 if you need urgent care.