Weight-loss guide

Tirzepatide starting dose: what the label prints

The Zepbound label says the recommended starting dosage is 2.5 mg injected subcutaneously once weekly for 4 weeks. That dose is for treatment initiation and is not approved as a maintenance dosage.

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What the label prints

Label start 2.5 mg injected subcutaneously once weekly for 4 weeks
Zepbound label, opened 2026-10-16. A compounded dose is a different prescription and is not covered here.
Zepbound label (Section 2.1)Plain version
“The recommended starting dosage of ZEPBOUND for all indications is 2.5 mg injected subcutaneously once weekly for 4 weeks.”The label start is 2.5 mg, once a week, for 4 weeks.
“The 2.5 mg dosage is for treatment initiation and is not approved as a maintenance dosage.”The first dose is a starting step, not the dose you stay on.

A clinician sets any dose and any change to it. A prescription is not automatic, and the clinician can say no. The Mounjaro label was not opened for this page.

Related: tirzepatide, semaglutide vs tirzepatide.

References

Opened 2026-10-16.

  1. DailyMed: Zepbound (tirzepatide) injection. Section 2.1, recommended starting dosage.

About Mendoxa

  • Mendoxa serves 49 U.S. states. Not available in California.
  • Licensed clinicians in the LocumTele network review every intake. The clinician can say no.
  • When a prescription is issued, Rush Pharmacy fulfills it.
  • A compounded medicine is not an FDA-approved finished product.
  • The price is shown in the intake, not on this page.
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