ED guide · Safety

Nitrates and ED medicines do not mix

The Viagra, Cialis, and vardenafil labels all say not to use them with nitrates or other nitric oxide donors. The same labels say not to use them with a guanylate cyclase stimulator such as riociguat. If you use a chest-pain medicine, tell the clinician before you start a visit.

Mendoxa ED care, reviewed by a licensed clinician before any prescription

What each label says

Position 1 for this query on 2026-10-16 is a journal page. We are not going to outrank that this month. The stop itself is on the labels.

Stop Nitrates and riociguat Tell the clinician Chest-pain medicines
Opened 2026-10-16. This is not a timing trick. The labels do not give a safe gap for a nitrate after these tablets.
MedicineLabel stop
SildenafilDo not use with nitric oxide donors, including organic nitrates or nitrites in any form. Do not use with riociguat.
TadalafilDo not use with any organic nitrate. Do not use with riociguat.
VardenafilDo not use with nitrates or nitric oxide donors. Do not use with riociguat.

Poppers are nitrates. They are the same stop. An online visit is not a way around a nitrate. If you have chest pain now, call 911. This page is not emergency care.

The molecule pages: sildenafil, tadalafil, vardenafil.

References

Opened 2026-10-16. A number that was not in these files is not on this page.

  1. DailyMed: Viagra (sildenafil citrate) tablets.
  2. DailyMed: Cialis (tadalafil) tablets.
  3. DailyMed: vardenafil hydrochloride tablets.

About Mendoxa

  • Mendoxa serves 49 U.S. states. Not available in California.
  • A licensed clinician can say no. A prescription is not automatic.
  • When a prescription is issued, Rush Pharmacy fulfills it.
  • A compounded medicine is not an FDA-approved finished product.
  • The price is shown in the intake, not on this page.
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